<![CDATA[The Effect of Antidiabetic Combination of Aqueous Extracts of Salam Leaves (Stevia Rebaudiana Bert.) and Bitter Leaves (Andrographis Folium) in White Male Mice]]>

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<![CDATA[The Effect of Antidiabetic Combination of Aqueous Extracts of Salam Leaves (Stevia Rebaudiana Bert.) and Bitter Leaves (Andrographis Folium) in White Male Mice]]> 'Ainun Naim Pengarang White male mice are grouped into six treatment groups: Normal control, negative controls (CMC-Na 0, 5%), positive control (metformin HCl dose of 20 mg/KgBW), SB 7, 5: 20, SB 15: 40, and SB 30: 80. All groups except normal control-induced alloxan dose of 200 mg/KgBW on day-0, treatment continued from day 1–day 24. The data obtained were blood glucose level of mice before and after treatment. Blood glucose level data were analyzed using Shapiro–Wilk test and continued by analysis of variance (ANOVA) with α= 0.01. Results The results showed that there was a decrease in blood glucose level a combination of aqueous extract salam leaves and bitter leaves at P< 0.01. Conclusion Combination of aqueous extract salam leaves and bitter leaves is able to lower blood glucose level in male white mice.